发明名称 Heterocylic antiviral compounds
摘要 This invention relates to piperidine derivatives of formula I wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as defined herein useful in the treatment of a variety of disorders, including those in which the modulation of CCR5 receptors is implicated. Disorders that may be treated or prevented by the present derivatives include HIV and genetically related retroviral infections (and the resulting acquired immune deficiency syndrome, AIDS), rheumatoid arthritis, solid organ transplant reject (graft vs. host disease), asthma and COPD.
申请公布号 US2008249087(A1) 申请公布日期 2008.10.09
申请号 US20080079746 申请日期 2008.03.28
申请人 ROTSTEIN DAVID MARK;MELVILLE CHRIS RICHARD 发明人 ROTSTEIN DAVID MARK;MELVILLE CHRIS RICHARD
分类号 A61K31/537;A61P9/00;A61P11/06;A61P19/02;A61P29/00;A61P31/18;C07D265/14 主分类号 A61K31/537
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