| 发明名称 |
1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE |
| 摘要 |
<p>Compounds of Formula (I) or a salt thereof are provided: wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, Q and Z are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders and cognitive impairments are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.</p> |
| 申请公布号 |
WO2008119716(A1) |
申请公布日期 |
2008.10.09 |
| 申请号 |
WO2008EP53595 |
申请日期 |
2008.03.27 |
| 申请人 |
GLAXO GROUP LIMITED;COOPER, DAVID GWYN;FORBES, IAN THOMSON;GARZYA, VINCENZO;WALKER, GRAHAM;WYMAN, PAUL ADRIAN |
发明人 |
COOPER, DAVID GWYN;FORBES, IAN THOMSON;GARZYA, VINCENZO;WALKER, GRAHAM;WYMAN, PAUL ADRIAN |
| 分类号 |
C07D401/04;A61K31/454;A61P25/00;C07D407/14 |
主分类号 |
C07D401/04 |
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