发明名称 NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTORS
摘要 The present invention relates to new compounds of formula (I) or salts, solvates or solvated salts thereof, wherein Q, X, Y, Z, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP> and m, n and p are defined as in claim 1, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions comprising said compounds and to the use of said compounds as modulators of chemokine receptor activity in the treatment of airway diseases, inflammatory diseases, COPD and asthma.
申请公布号 WO2008121066(A1) 申请公布日期 2008.10.09
申请号 WO2008SE50359 申请日期 2008.03.28
申请人 ASTRAZENECA AB;MENSONIDES-HARSEMA, MARGUERITE 发明人 MENSONIDES-HARSEMA, MARGUERITE
分类号 C07D491/107;A61K31/438;A61K31/444;A61K31/506;A61K31/517;A61P11/00;A61P11/06;A61P29/00;C07D401/14 主分类号 C07D491/107
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