COMBINED USE OF DIPEPTIDYL PEPTIDASE 4 INHIBITOR COMPOUND AND SWEETENER

摘要

It is intended to provide a novel therapeutic or preventive method which exhibits an excellent anti-obesity effect (an effect of reducing body fat an d/or an effect of reducing body fat) and a pharmaceutical composition, and u se thereof. The pharmaceutical composition comprising a dipeptidyl peptidase IV inhibitor compound and a sweetener having an action of promoting GLP-1 s ecretion in combination, and the use thereof in the production of a pharmace utical. Further, the therapeutic or preventive method for obesity, character ized by administering an effective amount of (a) a dipeptidyl peptidase IV i nhibitor compound and (b) a sweetener having an action of promoting GLP-1 se cretion to a patient with obesity symptoms.