发明名称 |
UTILITY OF HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGENIN DIAGNOSIS AND TREATMENT OF CANCER |
摘要 |
HMW-MAA antibody cocktails and their uses in detecting cancer and isolati ng cancer cells are disclosed. Also disclosed are methods of detecting cance r based on the presence of an HMW-MAA genomic sequence in circulating DNA, a s well as the increased expression of the HMW-MAA gene and the reduced methy lation of the HMW-MAA gene promoter in tissues and circulating cells.
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申请公布号 |
CA2682155(A1) |
申请公布日期 |
2008.10.09 |
申请号 |
CA20072682155 |
申请日期 |
2007.09.28 |
申请人 |
JOHN WAYNE CANCER INSTITUTE |
发明人 |
HOON, DAVE S.B.;WANG, XINHUI;GOTO, YASUFUMI;KITAGO, MINORU;FERRONE, SOLDANO |
分类号 |
C07K16/00;A61K48/00;C07K16/30;C12Q1/68;C40B30/04;C40B40/10;G01N33/53;G01N33/574 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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