| 发明名称 |
DIMERS OF HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF COPD |
| 摘要 |
Covalent conjugates of two or more compounds, each having a structure as defined in any of WO2004/043924, WO2005/021509, WO2005/021512, WO2005/026123, WO2005/026124, WO2006/098683 and WO2006/098684, are inhibitors of human neutrophil elastase, useful in treatment of, for example, chronic obstructive pulmonary disease. Dimers of formula (IA) or (IB): wherein LINKER and the variable substituents are particular types of such multimers. |
| 申请公布号 |
WO2007107706(A3) |
申请公布日期 |
2008.10.09 |
| 申请号 |
WO2007GB00919 |
申请日期 |
2007.03.16 |
| 申请人 |
ARGENTA DISCOVERY LIMITED;FINCH, HARRY;EDWARDS, CHRISTINE;RAY, NICHOLAS, CHARLES |
发明人 |
FINCH, HARRY;EDWARDS, CHRISTINE;RAY, NICHOLAS, CHARLES |
| 分类号 |
A61K47/48;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P29/02;C07D213/82;C07D401/12;C07D403/12 |
主分类号 |
A61K47/48 |
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