发明名称 |
METHOD FOR DETERMINATION OF CONDITION OF DISSEMINATED INTRAVASCULAR COAGULATION SYNDROME |
摘要 |
Disclosed is a method for determination of a condition of disseminated intravascular coagulation syndrome (DIC) in a DIC patient, wherein the method comprises determining the amount and/or the enzymatic activity of a von Willebrand factor (vWF)-cleaving enzyme (ADAMTS13) (preferably also the amount of vWF). Also disclosed is a kit for determination of a condition of DIC, wherein the kit comprises an antibody capable of binding specifically to ADAMTS13 or a fragment thereof. The method enables to achieve a differential diagnosis of a thrombotic thrombocytopenic purpura (TTP) patient from a DIC patient, which has been difficult to achieve previously only based on clinical observations or only by using conventional markers. |
申请公布号 |
KR20080091185(A) |
申请公布日期 |
2008.10.09 |
申请号 |
KR20087018908 |
申请日期 |
2007.01.30 |
申请人 |
KABUSHIKI KAISHA MITSUBISHI KAGAKU IATRON;JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
ONO TOMOKO;WATANABE SHINICHIRO;FURUSAKI FUMIO;IGAMI KO |
分类号 |
G01N33/573;C12Q1/37 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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