发明名称 COMBINATION OF A MEK- INHIBITOR AND A B-RAF INHIBITOR FOR THE TREATMENT OF CANCER
摘要 <p>This invention relates to a combination product comprising a MEK inhibitor and a B-raf inhibitor, and to methods for the production of an anti-cancer effect in a patient, which is accordingly useful in the treatment of cancer in a patient. More specifically the present invention relates to: a combination product comprising a MEK inhibitor and a B raf inhibitor; a combination product comprising a kit of parts comprising a MEK inhibitor and a B-raf inhibitor; use of the combination product in the treatment of cancer; a method of treating cancer comprising administering the combination product to a patient. The combination product and methods of the invention are also useful in the treatment of other diseases associated with the activity of MEK, and/or B-raf.</p>
申请公布号 WO2008120004(A1) 申请公布日期 2008.10.09
申请号 WO2008GB01184 申请日期 2008.04.02
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;ADJEI, ALEX;DREW, LISA;FRIDAY, BRET;GIBBS, JACKSON, B.;MCCOON, PATRICIA, ELIZABETH;SMITH, PAUL, DAVID;YU, CHUNRONG 发明人 ADJEI, ALEX;DREW, LISA;FRIDAY, BRET;GIBBS, JACKSON, B.;MCCOON, PATRICIA, ELIZABETH;SMITH, PAUL, DAVID;YU, CHUNRONG
分类号 A61K31/4184;A61K31/44;A61K31/4412;A61K31/4427;A61K31/50;A61K31/517;A61P35/00 主分类号 A61K31/4184
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