发明名称 |
Method for Improved Selection of Rnai Transfectants |
摘要 |
The present invention is directed to a method for inactivation of expression of a gene in a eucaryotic cell comprising (i) transfection of a eucaryotic cell with DNA comprising an expression cassette for expression of a cell surface protein and an expression cassette for expression of a RNAi compound, said compound being capable of inactivating expression of said gene, wherein said expression cassette for expression of a cell surface protein and said expression cassette for expression of a RNAi compound are located on the same vector DNA, and (ii) enrichment and/or selection of cells which express said cell surface protein.
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申请公布号 |
US2008248468(A1) |
申请公布日期 |
2008.10.09 |
申请号 |
US20050792902 |
申请日期 |
2005.12.13 |
申请人 |
KUBBIES MANFRED;MACEK ROBERT;RIES CAROLA |
发明人 |
KUBBIES MANFRED;MACEK ROBERT;RIES CAROLA |
分类号 |
C12Q1/68;C07K16/00;C12N15/11;C12N15/63 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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