发明名称 2(HYDROXYETHYL)TRIMETHYLAMMONIUM THIOCTATE (CHOLINE THIOCTATE) DISPLAYING HEPATOPROTECTIVE, HYPOAMMONIEMIC AND DETOXIC ACTION, A METHOD FOR ITS PRODUCTION AND A PHARMACEUTICAL COMPOSITION BASED THEREON
摘要 The invention relates to medicine and chemical and pharmaceutical industry, and more particularly to a new physiologically active substance 2(hydroxyethyl)trimethylammonium thioctate (choline thioctate) displaying hepatoprotective, hypoammoniemic and detoxic activity, to a method for producing said substance, and to pharmaceutical compositions based thereon. The technical result of implementing the invention is a new physiologically active chemical substance 2(hydroxyethyl)trimethylammonium thioctate (choline thioctate) displaying hepatoprotective, hypoammoniemic and detoxic activity, a method for producing the same which method ensures a higher level and a wider spectrum of specific activity while simplifying, and shortening the duration of the manufacturing process, and pharmaceutical compositions based on the new physiologically active substance 2(hydroxyethyl)trimethylammonium thioctate (choline thioctate) in various dosage forms the use whereof results in a diversified range of hepatoprotective drugs.
申请公布号 WO2008120070(A2) 申请公布日期 2008.10.09
申请号 WO2008IB00727 申请日期 2008.03.17
申请人 AKTSIONERNE TOVARYSTVO VIDKRYTOGO TYPU =GALYCHFARM=;TOVARYSTVO Z OBMEZHENOYU VIDPOVIDALNISTYU =INSTYTUT FITO-HIMICHNYH TEHNOLOGIJ=;VIDKRYTE AKTSIONERNE TOVARYSTVO =KYIVMEDPREPARAT=;NOVIK, IVAN IVANOVYCH 发明人 NOVIK, IVAN IVANOVYCH
分类号 C07D339/04 主分类号 C07D339/04
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