发明名称 |
RNA INTERFERENCE AGAINST WRAP53 TO TREAT HYPERPROLIFERATIVE DISEASES |
摘要 |
A small nucleic acid molecule that down-regulates expression of Wrap53 gene via RNA interference (RNAi), wherein at least one strand of said small nucleic acid molecule is about 15 to about 30 nucleotides in length; and wherein at least one strand of said small nucleic acid molecule comprises a nucleotide sequence having sufficient complementarity to an RNA of said Wrap53 gene for the small nucleic acid molecule to direct cleavage of said RNA via RNA interference, for use as a medicament. |
申请公布号 |
WO2008041933(A3) |
申请公布日期 |
2008.10.09 |
申请号 |
WO2007SE50692 |
申请日期 |
2007.10.01 |
申请人 |
APREA AB;FARNEBO, MARIANNE;MAHMOUDI, SALAH;WIMAN, KLAS |
发明人 |
FARNEBO, MARIANNE;MAHMOUDI, SALAH;WIMAN, KLAS |
分类号 |
A61K31/7105;A61P35/00;C12N15/113 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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