发明名称 |
MODIFIED CLOSTRIDIAL TOXINS WITH ENHANCED TRANSLOCATION CAPABILITIES AND ALTERED TARGETING ACTIVITY FOR CLOSTRIDIAL TOXIN TARGET CELLS |
摘要 |
The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain, a translocation facilitating domain and an altered target domain; polynucleotide molecules encoding such modified Clostridial toxins; and methods of producing such modified Clostridial toxins.
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申请公布号 |
US2008241881(A1) |
申请公布日期 |
2008.10.02 |
申请号 |
US20070776052 |
申请日期 |
2007.07.11 |
申请人 |
STEWARD LANCE E;FRANCIS JOSEPH;FERNANDEZ-SALAS ESTER G;GILMORE MARCELLA A;LI SHENGWEN;AOKI KEI ROGER |
发明人 |
STEWARD LANCE E.;FRANCIS JOSEPH;FERNANDEZ-SALAS ESTER G.;GILMORE MARCELLA A.;LI SHENGWEN;AOKI KEI ROGER |
分类号 |
C12P21/00;C07H21/00;C12N9/00 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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