发明名称 |
FUSION PROTEIN CAPABLE OF DEGRADING AMYLOID BETA PEPTIDE |
摘要 |
<p>The present invention relates fusion proteins and their use in enzymatic treatment of Alzheimer's disease patients. Said fusion protein has the formula M-A, capable of degrading amyloid beta peptide at one or more cleavage sites in its amino acid sequence, wherein M is a protein componentthat prolongs the half-life of the fusion protein, and A is a protein component that cleaves the amyloid beta peptide.</p> |
申请公布号 |
WO2008118093(A1) |
申请公布日期 |
2008.10.02 |
申请号 |
WO2008SE50346 |
申请日期 |
2008.03.27 |
申请人 |
ASTRAZENECA AB;ANDERSSON, CHRISTIN;FRESKGAARD, PER-OLA |
发明人 |
ANDERSSON, CHRISTIN;FRESKGAARD, PER-OLA |
分类号 |
A61K47/48;A61K38/48;A61P25/28;C07K19/00;C12N9/64 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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