发明名称 Compositions and methods for ameliorating hyperlipidemia
摘要 The invention provides compositions and methods for treating hyperlipidemia by administering a Microsomal Triglyceride Transfer Protein (MTP) inhibitor in combination with a Liver Fatty Acid-Binding Protein (L-FABP) inhibitor, methods of preventing the development of hepatic steatosis, methods of identifying an agent useful for treating hyperlipidemia, and methods of screening for inhibitors of MTP and L-FABP activity. Also provided are pharmaceutical compositions comprising a MTP inhibitor and a L-FABP inhibitor.
申请公布号 US2008241869(A1) 申请公布日期 2008.10.02
申请号 US20070809870 申请日期 2007.06.01
申请人 SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION 发明人 DAVIS ROGER A.
分类号 A61K31/7105;C12Q1/02 主分类号 A61K31/7105
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