| 发明名称 |
Use of Biocistronic DNA Constructs for Identifying Compounds that Inhibit IRES-Dependent Translation |
| 摘要 |
The present invention relates to use of bicistronic DNA constructs for identifying compounds that inhibits IRES-dependent translation activity of an infectious enterovirus (EV) or encephalomyocarditis virus (EMCV) without affecting CAP-dependent translation activity of a host subject. The compounds thus identified are useful in preparation of a medicament for treating EV or EMCV infection.
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| 申请公布号 |
US2008242734(A1) |
申请公布日期 |
2008.10.02 |
| 申请号 |
US20070781564 |
申请日期 |
2007.07.23 |
| 申请人 |
CHUNG YUAN CHRISTIAN UNIVERSITY |
发明人 |
WU TZONG-YUAN;ZENG SHIN-JHAN;CHEN YING-JU;HSU TSU-AN;SHIH SHIN-RU;KAO SUEY-SHENG;JINN TZYY-RONG |
| 分类号 |
A61K31/13;A61P25/24 |
主分类号 |
A61K31/13 |
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