发明名称 |
Pharmaceutical Composition |
摘要 |
Stabilized pharmaceutical compositions comprising polymorphs of active pharmaceutical ingredients susceptible to conversion to alternate polymorph forms are prepared by a process of wet granulation in which the ratios of active, fillers, and granulating liquid are controlled in order to avoid polymorphic interconversions.
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申请公布号 |
US2008242725(A1) |
申请公布日期 |
2008.10.02 |
申请号 |
US20050590780 |
申请日期 |
2005.02.28 |
申请人 |
KERC JANEZ;SVETE PETER;JERALA-STRUKELJ ZDENKA;HUMAR VLASTA;GRAHEK ROK;HUSU-KOVACEVIC BREDA |
发明人 |
KERC JANEZ;SVETE PETER;JERALA-STRUKELJ ZDENKA;HUMAR VLASTA;GRAHEK ROK;HUSU-KOVACEVIC BREDA |
分类号 |
A61K31/225;A61K9/16;A61K9/28;A61K31/4184;A61K31/695;A61K47/26;A61P9/10;C07C67/48;C07C67/62;C07D403/10 |
主分类号 |
A61K31/225 |
代理机构 |
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代理人 |
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地址 |
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