发明名称 MULTI-TARGETING SHORT INTERFERING RNAs
摘要 The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are designed to incorporate features of siRNA molecules and features of micro-RNA (miRNA) molecules. In another embodiment, multi-targeting siRNA molecules are designed so that each strand is directed to separate targets.
申请公布号 US2008242632(A1) 申请公布日期 2008.10.02
申请号 US20080021604 申请日期 2008.01.29
申请人 CITY OF HOPE 发明人 ROSSI JOHN J.;SNOVE OLA;EHSANI ALI;SAETROM PAL;HOEHN BRITTA
分类号 A61K31/7105;A61P9/00;A61P29/00;A61P31/18;A61P35/04;C07H21/02 主分类号 A61K31/7105
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