发明名称 |
3-H-PYRAZOLOPYRIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME |
摘要 |
The invention relates to 3-H-pyrazolopyridines according to the general formula (I) in which A, B, D, E, R<SUP>a</SUP>, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP> and q are as defined in the claims, and salts, N-oxides, solvates and prodrugs thereof, to pharmaceutical compositions comprising said 3-H-pyrazolopyridine compounds, to methods of preparing said 3-H-pyrazolopyridines, to intermediate compounds useful in said methods, to uses of said intermediate compounds in the preparation of said 3-H-pyrazolopyridines, as well as to uses of said 3-H-pyrazolopyridines for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling. |
申请公布号 |
WO2008071456(A3) |
申请公布日期 |
2008.10.02 |
申请号 |
WO2007EP11282 |
申请日期 |
2007.12.14 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT;HARTUNG, INGO;KETTSCHAU, GEORG;SCHUMANN, INGRID;THIERAUCH, KARL-HEINZ;BOEMER, ULF |
发明人 |
HARTUNG, INGO;KETTSCHAU, GEORG;SCHUMANN, INGRID;THIERAUCH, KARL-HEINZ;BOEMER, ULF |
分类号 |
C07D471/04;A61K31/437;A61P29/00;A61P35/00 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|