发明名称 |
6-MODIFIED BICYCLIC NUCLEIC ACID ANALOGS |
摘要 |
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either(R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance. |
申请公布号 |
KR20080088662(A) |
申请公布日期 |
2008.10.02 |
申请号 |
KR20087020907 |
申请日期 |
2007.01.27 |
申请人 |
ISIS PHARMACEUTICALS INC. |
发明人 |
SWAYZE ERIC E.;SETH PUNIT P. |
分类号 |
C07H19/04;C07H21/00 |
主分类号 |
C07H19/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|