发明名称 |
A pharmaceutical composition comprising an immunoglobulin Fc region as a carrier |
摘要 |
Disclosed is a novel use of an immunoglobulin Fc fragment, and more particularly, a pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier. The pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier remarkably extends the serum half-life of a drug while maintaining the in vivo activity of the drug at relatively high levels. Also, when the drug is a polypeptide drug, the pharmaceutical composition has less risk of inducing immune responses compared to a fusion protein of the immunoglobulin Fc fragment and a target protein, and is thus useful for developing long-acting formulations of various polypeptide drugs. |
申请公布号 |
AU2004282985(B8) |
申请公布日期 |
2008.10.02 |
申请号 |
AU20040282985 |
申请日期 |
2004.11.13 |
申请人 |
HANMI PHARMACEUTICAL CO., LTD. |
发明人 |
CHANG HWAN KIM;DAE HAE SONG;IN YOUNG CHOI;GWAN SUN LEE;SUNG YOUB JUNG;YOUNG MIN KIM;SE CHANG KWON |
分类号 |
A61K47/42;C07K19/00;C07K16/00;C07K16/42;C12N15/70 |
主分类号 |
A61K47/42 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|