| 摘要 |
A cellular stent carries living therapeutic cellular material for implantation into a human or animal body and allows either localized or systemic delivery of the therapeutic products, while promoting engraftment, either on a tissue surface or its interior. The cells are contained within wells in the stent that are enclosed by inner and outer membranes that seal the cellular material within the stent until it is to be released. The outer membrane is preferably in the form of a thin, hard plastic sheet having a plurality of score lines, perforations, or other lines or weakening provided therein. The membrane may be embedded in a softer perimetral mount which retains it in position until the seal is to be broken. Rupture of the outer membrane ensures penetration of the cells into the interior of tissue or an organ in which the stent is implanted.
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