NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE

摘要

A novel (2-aminophenyl)pyridinecarboxamide derivative having a novel urea structure is synthesized, which has pharmacological activity. The derivative is a compound represented by the formula (1) or a salt thereof. In the formula, R¹ and R² each represents hydrogen, lower alkyl, etc.; R³ represents hydroxy, lower alkoxy, lower cycloalkyloxy, aryloxy, carboxy, lower alkoxycarbonyl, -OCONR^aR^b, -NR^cR^d, etc.; R⁴ and R⁵ each represents halogeno, lower alkyl, hydroxy, lower alkoxy, etc.; R^a and R^b each represents hydrogen, lower alkyl, lower cycloalkyl, aryl, heterocyclic group, etc.; R^c and R^d each represents hydrogen, lower alkyl, lower cycloalkyl, aryl, etc.; X represents lower alkylene; Y represents a single bond or lower alkylene; W¹-W² represents N-C or C-N; and l and m each is 0, 1, 2, or 3. [Chemical formula 1] (1)