| 发明名称 |
TRIAZOLONE DERIVATIVE. |
| 摘要 |
<p>Compounds of the general formula (1), salts thereof and their hydrates. (1) In the formula, each of R1a, R1b, R1c and R1d independently is a hydrogen atom, etc. R2 is an optionally substituted phenyl, etc. R3 is an optionally substituted C6-10 aryl, etc. Each of Z1 and Z2 independently is a hydrogen atom. They are useful as a therapeutic agent and/or preventive for diseases caused by clot formation, being safer, and have appropriate physicochemical stability.</p> |
| 申请公布号 |
MX2008012031(A) |
申请公布日期 |
2008.10.02 |
| 申请号 |
MX20080012031 |
申请日期 |
2007.03.22 |
| 申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
NAGAKURA, TADASHI;OMAE, TAKAO;HIROTA, SHINSUKE;KUSANO, KAZUTOMI;CLARK, RICHARD;MATSUURA, FUMIYOSHI;KIRA, KAZUNOBU;AZUMA, HIROSHI;HORIZOE, TATSUO;TABATA, KIMIYO;INOUE, ATSUSHI |
| 分类号 |
C07D249/12;A61K31/4196;A61K31/427;A61K31/4439;A61K31/444;A61K31/497;A61K31/501;A61K31/506;A61K31/538;A61P7/02;A61P9/10;A61P11/00;A61P35/00;C07D401/04;C07D401/14;C07D403/04;C07D405/14;C07D409/04;C07D413/14;C07D417/04 |
主分类号 |
C07D249/12 |
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