发明名称 |
OSCILLATING CELL CULTURE BIOREACTOR |
摘要 |
Methods and devices for cell or tissue culture are provided. One aspect provides a bioreactor having a gas permeable, closed-loop chamber for cell or tissue culture, and an oscillating means for moving the gas permeable, closed-loop chamber bidirectionally along an axis horizontal to an axis normal to the closed-loop chamber to force convection of cells and fluid in the gas permeable, closed-loop chamber. The bioreactor optionally includes a tissue engineering scaffold, an inlet means, an outlet means, and integrated sensors. Another aspect provides a bioreactor having a plurality of gas permeable, closed-loop chambers for cell or tissue culture. Methods of culturing cells and producing tissue constructs are also provided. |
申请公布号 |
WO2008098165(A3) |
申请公布日期 |
2008.10.02 |
申请号 |
WO2008US53411 |
申请日期 |
2008.02.08 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;MORETTI, MATTEO G.;FREED, LISA E.;LANGER, ROBERT S. |
发明人 |
MORETTI, MATTEO G.;FREED, LISA E.;LANGER, ROBERT S. |
分类号 |
C12M1/02 |
主分类号 |
C12M1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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