发明名称 CANCER DISEASE MODIFYING ANTIBODY 010207-01 PRODUCED BY HYBRIDOMA CELL LINE AR51A630.3.
摘要 <p>The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.</p>
申请公布号 WO2008116299(A1) 申请公布日期 2008.10.02
申请号 WO2008CA00553 申请日期 2008.03.25
申请人 ARIUS RESEARCH INC. 发明人 YOUNG, DAVID S.F.;FINDLAY, HELEN, P.;HAHN, SUSAN, E.;CECHETTO, LISA, M.
分类号 C12N5/18;A61K39/395;A61K47/48;A61K51/10;A61P35/00;A61P37/04;C07K16/30;C07K16/46;C07K19/00;C12N5/12;C12P21/08;G01N33/574;G01N33/577 主分类号 C12N5/18
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