发明名称 |
SOLID FIBRINOGEN PREPARATION |
摘要 |
Disclosed is a fibrinogen preparation which has improved solubility, can be prepared within a short time, and can be used rapidly in clinical practic e. Also disclosed is a tissue adhesive agent comprising the preparation. Spe cifically disclosed is a solid fibrinogen preparation mainly comprising fibr inogen, and further containing albumin, an nonionic surfactant, a basic amin o acid or a salt thereof, and at least two amino acids or salts thereof sele cted from an acidic amino acid or a salt thereof and a neutral amino acid or a salt thereof. The solid fibrinogen preparation may be immobilized onto a medical substrate to produce a fibrinogen-immobilized substrate. The fibrino gen-immobilized substrate may be used in combination with a component mainly composed of thrombin to produce a fibrin adhesive agent.
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申请公布号 |
CA2682173(A1) |
申请公布日期 |
2008.10.02 |
申请号 |
CA20082682173 |
申请日期 |
2008.03.21 |
申请人 |
JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
HAMURO, TSUTOMU;KAETSU, HIROSHI;OKUDA, MIKA;ARAKI, TATSUYA;MIYAGAWA, SHINICHI |
分类号 |
A61K38/43;A61K9/19;A61K9/70;A61K47/18;A61K47/42;A61L15/64;A61L26/00 |
主分类号 |
A61K38/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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