CONFORMATIONALLY RESTRAINED EPOTHILONE ANALOGUES AS ANTI-LEUKEMIC AGENTS
摘要
A method for synthesizing anti-leukemic epothilone analogues includes rigidifying a region between the macrolactone ring and the aromatic side-chain. The anti-leukemic compositions are non-naturally occurring epothilone analogue that are rigidified between the macrolactone ring and the aromatic side-chain.
申请公布号
WO2008118327(A1)
申请公布日期
2008.10.02
申请号
WO2008US03638
申请日期
2008.03.20
申请人
UNIVERSITY OF TOLEDO;TILLEKERATNE, VIRANGA;HUDSON, RICHARD, A.;ALHAMADSHEH, MAMOUN
