| 摘要 |
Carbon- linked tetrahydro-pyrazolo-pyridine compounds of formula (I) are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis. |
| 申请人 |
SUNESIS PHARMACEUTICALS, INC.;AMERIKS, MICHAEL, K.;AXE, FRANK, U.;CAI, HUI;EDWARDS, JAMES, P.;GLEASON, ELIZABETH, ANN;GRICE, CHERYL, A.;MEDUNA, STEVEN, P.;TAYS, KEVIN, L.;WICKBOLDT, ALVAH, T.;WIENER, JOHN, J.M. |
发明人 |
AMERIKS, MICHAEL, K.;AXE, FRANK, U.;CAI, HUI;EDWARDS, JAMES, P.;GLEASON, ELIZABETH, ANN;GRICE, CHERYL, A.;MEDUNA, STEVEN, P.;TAYS, KEVIN, L.;WICKBOLDT, ALVAH, T.;WIENER, JOHN, J.M. |
