摘要 |
Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 ("Hsp90").
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申请人 |
INFINITY DISCOVERY, INC.;AUSTAD, BRIAN, C.;GRENIER, LOUIS;HOLSON, EDWARD, B.;LEE, JOHN, J.;PAK, ROGER, H.;PORTER, JAMES, R.;WRIGHT, JAMES, L. |
发明人 |
AUSTAD, BRIAN, C.;GRENIER, LOUIS;HOLSON, EDWARD, B.;LEE, JOHN, J.;PAK, ROGER, H.;PORTER, JAMES, R.;WRIGHT, JAMES, L. |