发明名称 Novel Apo2L and IL-24 Polypeptides, Polynucleotides, and Methods of Their Use
摘要 Disclosed are newly identified Interleukin 24 and APO2L splice variant molecules, their polypeptide sequences, and the polynucleotides encoding the polypeptide sequences. Also provided is a procedure for producing such polypeptides by recombinant techniques employing, for example, vectors and host cells, and, for example, heterologous secretory leader sequences. Also disclosed are methods for using such polypeptides and modulators thereof for the treatment of diseases, including cancer, immune diseases, infectious diseases, and ischemic diseases.
申请公布号 US2008242603(A1) 申请公布日期 2008.10.02
申请号 US20050589561 申请日期 2005.02.18
申请人 WANG YAN;TSUI COLLINS AMY L;HESTIR KEVIN;LEE ERNESTINE;HALENBECK FORGAN ROBERT;BOSCH ELIZABETH;LINNEMANN THOMAS;WILLIAMS LEWIS THOMAS 发明人 WANG YAN;TSUI COLLINS AMY L.;HESTIR KEVIN;LEE ERNESTINE;HALENBECK FORGAN ROBERT;BOSCH ELIZABETH;LINNEMANN THOMAS;WILLIAMS LEWIS THOMAS
分类号 A61K38/17;A61P35/00;C07H21/00;C07K14/00;C07K14/54;C07K14/705;C12N5/06;C12N15/09 主分类号 A61K38/17
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