发明名称 |
Two component bacillus lantibiotic and methods for producing and using the same |
摘要 |
The present invention relates to two-component lantibiotics isolated from Bacillus sp. Methods for producing said lantibiotics are provided, wherein dehydration and cyclization of the peptides is carried out by two substrate-specific modifying enzymes. Given the antimicrobial activity of the instant lantibiotics, methods for preventing or treating bacterial infections are also provided.
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申请公布号 |
US2008242617(A1) |
申请公布日期 |
2008.10.02 |
申请号 |
US20070931888 |
申请日期 |
2007.10.31 |
申请人 |
VAN DER DONK WILFRED A;COOPER LISA E;MCCLERREN AMANDA L |
发明人 |
VAN DER DONK WILFRED A.;COOPER LISA E.;MCCLERREN AMANDA L. |
分类号 |
A61K38/10;C07H21/00;C07K7/08;C12N1/20;C12N9/50;C12N15/00;C12P21/06 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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