| 摘要 |
<p>This invention discloses novel gamma secretase inhibitors of the formula: R2and R3, or R2 and R4, or R3 and R4, together with the atoms to which they are bound, can form a fused cycloalkyl or fused heterocycloalkyl ring. The cycloalkyl ring or the heterocycloalkyl ring can be optionally substituted with one or more substituents. One or more compounds of formula (I), or formulations comprising such compounds, may be useful, e.g. in treating Alzheimer's Disease.</p> |
| 申请人 |
SCHERING CORPORATION. |
发明人 |
ASBEROM, THEODROS;ASBEROM, THEODROS;XU, RUO;QIANG, LI;BURNETT, DUANE A.;CLADER, JOHN W.;SU, JING;CAPLEN, MARY ANN;PISSARNITSKI, DMITRI A.;JOSIEN, HUBERT B.;ZHAO, ZHIQIANG;MCBRIAR, MARK D.;LI, HONGMEI;TANG, HAIQUN;KNUTSON, CHAD E.;WU, WEN-LIAN;BARA, THOMAS;BENNETT, CHAD E.;COLE, DAVID J.;DOMALSKI, MARTIN S.;RAJAGOPALAN, MURALI;SASIKUMAR, THAVALAKULAMGAR K. |
