发明名称 Benzo[d]imidazol analogs as vanilloid receptor ligands and their use in treatments
摘要 Substituted benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
申请公布号 US7429608(B2) 申请公布日期 2008.09.30
申请号 US20060337188 申请日期 2006.01.20
申请人 AMGEN INC. 发明人 NORMAN MARK H.;OGNYANOV VASSIL I.;WANG XIANGHONG
分类号 A61K31/416;C07D235/30 主分类号 A61K31/416
代理机构 代理人
主权项
地址