发明名称 Furo[2.3-b]pyridine derivatives for the treatment of hyper-proliferative disorders
摘要 This invention relates to a compound of Formula (I) wherein Y is CH or N; Ar<SUP>1 </SUP>is phenyl or pyridyl each optionally substituted with 1 or 2 substituents each selected independently from (C<SUB>1</SUB>-C<SUB>3</SUB>)alkoxy halo, OH, CF<SUB>3</SUB>, CN, NO<SUB>2 </SUB>and (C<SUB>1</SUB>-C<SUB>3</SUB>)alkyl, said alkyl being optionally substituted with CF<SUB>3</SUB>; Ar<SUP>2 </SUP>is phenyl or pyridyl each optionally substituted with 1 or 2 substituents each independently selected from halo, OH, CN, NO<SUB>2</SUB>, CF<SUB>3</SUB>, (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy, NR<SUP>1</SUP>R<SUP>1</SUP>, S(O)<SUB>2</SUB>R<SUP>2</SUP>, C(O)R<SUP>3</SUP>, and (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl optionally substituted with R<SUP>4</SUP>, and its use in treating hyper-proliferative disorders.
申请公布号 US7429584(B2) 申请公布日期 2008.09.30
申请号 US20040515605 申请日期 2004.11.23
申请人 BAYER PHARMACEUTICALS CORPORATION 发明人 ZHANG CHENGZHI;LADOUCEUR GAETAN;BURKE MICHAEL J.
分类号 C07D491/048;A61K31/4355;A61K31/436;A61K31/4375;A61K31/4741;A61K31/496;A61K31/505;A61K31/519;A61K31/5377;A61P13/10;A61P35/00;A61P35/02;A61P35/04;C07D401/06;C07D413/06;C07D491/04;C07D491/14;C07D491/153 主分类号 C07D491/048
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