发明名称 LO-CD2A ANTIBODY AND USES THEREOF FOR INHIBITING T CELL ACTIVATION AND PROLIFERATION
摘要 The present invention relates to a LO-CD2a antibody and methods of using suc h antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.
申请公布号 CA2295604(C) 申请公布日期 2008.09.30
申请号 CA19972295604 申请日期 1997.07.18
申请人 UNIVERSITE CATHOLIQUE DE LOUVAIN;BIOTRANSPLANT, INC. 发明人 LATINNE, DOMINIQUE;KAPLAN, RUTH;POSTEMA, CHRISTINA E.;KIEBER-EMMONS, THOMAS;BAZIN, HERVE;WHITE-SCHARF, MARY E.
分类号 C07K16/28;C12N15/09;A61K38/00;A61K39/395;A61P37/06;C07K16/46;C12P21/08 主分类号 C07K16/28
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