摘要 |
<p>PURIFICATION PROCESS Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula (I), in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 1000C and reduced pressure, e.g. 0.2 mbar, and recovering the purified product in free base or acid addition salt form.</p> |