ANTI-VEGF ANTIBODIES Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with nave libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the synthetic antibodies in research, diagnostic and therapeutic applications.
申请公布号
SG145725(A1)
申请公布日期
2008.09.29
申请号
SG20080058976
申请日期
2004.07.30
申请人
GENENTECH, INC.
发明人
FUH, GERMAINE;GERBER, HANSPETER;LIANG, WEI-CHING;FELLOUSE, FREDERIC, A.;SIDHU, SACHDEV, S.;WIESMANN, CHRISTIAN