发明名称 PREPARATION OF BIORESORBABLE MICROSPHERES OF POLYMER POLY (DL-LACTIDE-CO-GLYCOLIDE) CONTAING ASCORBIC ACID
摘要 Solution of poly (DL-lactide-co-glycolides) in acetone is added a water solution or a fine powdered ascorbic acid so as to obtain micro capsules DLPLG/ ascorbic acid in the ratio of 85/15%, 70/30%, 50/50% and 30/70%, respectively. Introduction of up to 15% of scorbic acid impacts in no way the increase in the particles DLPLG while further incerease, adds to the increase of dimensions thereof. Upon the precipitation with alcohol methanol or ethanol, the particles are stabilized by zeta potential forming PVA and then centirfuged, decanted and dried.
申请公布号 RS20060542(A) 申请公布日期 2008.09.29
申请号 RSP20060542 申请日期 2006.09.27
申请人 INSTITUT TEHNICKIH NAUKA SRPSKE AKADEMIJE NAUKA IUMETNOSTI 发明人 USKOKOVIC DRAGAN;STEVANOVC MAGDALENA
分类号 A61K9/52;A61K9/58;A61K31/375 主分类号 A61K9/52
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