发明名称 |
Method for the diagnosis of cancers by measuring the changes of glycosylation of TIMP-1 related to tumorigenesis and metastasis |
摘要 |
<p>The present invention relates to a method for diagnosing cancers by measuring proteins associated with tumorigenesis and metastasis, and more particularly provides a method for diagnosing cancers by measuring the changes of glycosylation of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), and a kit for diagnosis of cancers using the said method. The method and kit of the present invention can effectively be used for the sensitive diagnosis of cancers comprising colon cancer, stomach cancer, lung cancer and liver cancer.</p> |
申请公布号 |
EP1972939(A1) |
申请公布日期 |
2008.09.24 |
申请号 |
EP20080006160 |
申请日期 |
2002.12.28 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
KO, JEONG HEON;HWANG, SOO YOUNG;SOHN, HOSUNG;OH, SEJEONG;LEE, JEONG HWA;LEE, SANG CHUL;YOO, JONG-SHIN;LEE, DAE-SIL |
分类号 |
C07K7/06;G01N33/574;C07K7/08;G01N21/78;G01N33/53;G01N33/543 |
主分类号 |
C07K7/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|