| 摘要 |
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens. |
| 申请人 |
DUKE UNIVERSITY;THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
HAYNES, BARTON, F.;GAO, FENG;KORBER, BETTE, T.;HAHN, BEATRICE, H.;SHAW, GEORGE, M.;KOTHE, DENISE;LI, YING YING;DECKER, JULIE;LIAO, HUA-XIN |
