发明名称 |
BACTERIAL PRODUCTION OF HYDROPHOBIC POLYPEPTIDES |
摘要 |
Methods for the production of interferon- beta polypeptides by bacterial cells, by culturing cells capable of producing IFN- beta polypeptide under conditions that induce increased production of IFN- beta polypeptide. Such conditions include, for example, low potassium cation concentration and/or very low sodium cation concentration and/or specific pH ranges. |
申请公布号 |
WO9639523(A2) |
申请公布日期 |
1996.12.12 |
申请号 |
WO1996US09155 |
申请日期 |
1996.06.05 |
申请人 |
CHIRON CORPORATION |
发明人 |
DORIN, GLENN;MCALARY, PATRICK, J.;WONG, KATHLEEN, M. |
分类号 |
C12N15/09;A61K38/21;C07K14/565;C12N1/21;C12N15/22;C12P21/02;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|