发明名称 METHOD FOR OBTAINING 9-PHENYL-3,6-DIAZATRICYCLO[4.3.1.13,8]UNDECAN
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to method for obtaining a new compound, i.e. 9-phenyl-3,6-diazatricyclo[4.3.1.13,8]undecan with formula . Compounds of class of 3,6-diazahomoadamantan have anti-virus action comparable to that of aminoadamantan, demonstrate strychnine-like activity, have bactericidal, fungicidal and analgicidal properties. According to the present method, 1-(phenyltio)-3,6-diazatricycio[4.3.1.13,8]undecan-9-on(1) is subjected to interaction with phenyllithium in absolute ether to obtain 9-phenyl-1-(phenyltio)-3,6-diazatricyclo[4.3.1.13,8]undecan-9-ol (2) which is de-sulfated with Rene nickel when boiling in isopropyl alcohol. Yield comprises 76%. ^ EFFECT: obtaining a compound that has anti-virus action comparable to that of aminoadamantan, demonstrates strychnine-like activity, and has bactericidal, fungicidal and analgicidal properties. ^ 1 cl, 2 ex
申请公布号 RU2333911(C1) 申请公布日期 2008.09.20
申请号 RU20070111378 申请日期 2007.03.29
申请人 MOSKOVSKAJA GOSUDARSTVENNAJA AKADEMIJA TONKOJ KHIMICHESKOJ TEKHNOLOGII IM. M.V. LOMONOSOVA 发明人 KUZNETSOV ANATOLIJ IVANOVICH;SHUKKUR AKHMED KHAMED
分类号 C07D487/18 主分类号 C07D487/18
代理机构 代理人
主权项
地址