IL-17C ANTAGONISTS AND METHODS OF USING THE SAME

摘要

The present invention relates IL-17RE antagonists, such as soluble receptors and anti-IL-17RE antibodies, which are useful in blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17C. IL-17C is a cytokine that is involved in inflammatory processes and human disease. IL-17RE is a receptor for IL-17C. The present invention includes soluble IL-17RE, soluable fusion peptide comprising one or more IL-17RE domains anti-IL-17RE antibodies and binding partners, as well as methods for antagonizing IL-17C using such soluble receptors, antibodies and binding partners.