A COMPOSITION FOR THE TREATMENT OF A MASTITIS COMPRISING NATURAL PROTEINASE AND SILVER NANOPARTICLE COLLOIDAL SOLUTIONS AND TREATMENT USING THE SAME

摘要

A composition for treating mastitis of mammal comprising a natural proteinase or a pharmaceutically acceptable carrier and a silver nanoparticle colloidal solution is provided to show no systemic side effects, exhibit excellent stability, to require no additional withdrawal time for injection into a breast and contribute to construct environmental dairy industry. A composition for treating mastitis of mammal comprises 0.1-5 wt.% of a natural proteinase such as trypsin, alpha-chymotrypsin, pancreas, and bromelain and a silver nanoparticle colloidal solution or a pharmaceutically acceptable carrier, wherein the silver nanoparticle colloidal solution includes at least one polymer stabilizer selected from the group consisting of polyvinylpyrrolidone, (1-vinyl pyrrolidone)-acrylic acid copolymer, polyoxyethylene stearate, and 1-vinylpyrrolidone-vinyl acetic acid copolymer.