发明名称 |
KpnI Restriction Endonucleases with Reduced Star Activity |
摘要 |
Methods are provided for making restriction endonucleases with reduced star activity by one or more targeted mutations to a catalytic site within the restriction endonuclease. Examples of modifications to restriction endonucleases with significant sequence identity with KpnI are provided and reduced star activity demonstrated.
|
申请公布号 |
US2008227133(A1) |
申请公布日期 |
2008.09.18 |
申请号 |
US20060065384 |
申请日期 |
2006.08.18 |
申请人 |
INDIAN INSTITUTE OF SCIENCE;NEW ENGLAND BIOLABS, INC. |
发明人 |
NAGARAJA VALAKUNJA;SARAVANAN MATHESHWARAN;ZHU ZHENYU |
分类号 |
C12Q1/34;C12N5/06;C12N9/22;C12N15/11 |
主分类号 |
C12Q1/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|