TRANSFECTION IN ELECTRONICALLY DRIVEN CONTINUOUS FLOW

摘要

Biological cells and other membranous structures are transfected in a flow-through system by using a moving charge pattern on a longitudinal wall of a channel to cause the cells to travel through the channel due to an electrostatic interaction between the cells and the moving charge pattern. As the cells travel through the channel, they pass a transmitter that emits transfection energy sufficient to make the cell membranes permeable such that exogenous species in the fluid in which the cells are suspended will enter the cell interiors.