发明名称 |
Lactam-containing compounds and derivatives thereof as factor xa inhibitors |
摘要 |
The present application describes lactam-containing compounds and derivatives thereof of Formula I: P 4 -P-M-M- 4 or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa. |
申请公布号 |
AU2008207537(A1) |
申请公布日期 |
2008.09.18 |
申请号 |
AU20080207537 |
申请日期 |
2008.08.26 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
DONALD PINTO;YUN-LONG LI;MIMI QUAN;WEI HAN;MICHAEL ORWAT;PATRICK LAM;JENNIFER QIAO;STEPHANIE KOCH |
分类号 |
C07D401/10;A61K31/437;A61K31/4439;A61K31/444;A61K31/4545;A61K31/506;A61K31/517;A61K31/55;A61K31/553;A61P7/02;A61P9/00;C07D401/12;C07D401/14;C07D413/14;C07D471/04;C07D471/16 |
主分类号 |
C07D401/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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