发明名称 NOVEL PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR NEUROGENIC PAIN
摘要 <p>Disclosed is an excellent prophylactic and/or therapeutic agent for neurogenic pain, which comprises a 2-[(substituted-indene-7-yloxy)methyl]morpholine represented by the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The prophylactic and/or therapeutic agent is particularly useful as a prophylactic and/or therapeutic agent for a pain associated with allodynia, algesthesia, hyperesthesia, spontaneous pain, cancer pain, trigeminal neuralgia, phantom limb pain, post-herpetic pain, fibromyalgia, low back/leg pain, thalamic pain, entrapment (compression) peripheral neuropathy, atypical facial pain or spinal cord injury, a pain associated with multiple sclerosis, a pain associated with chemotherapy-induced neuropathy, cancer pain against which a narcotic analgesic agent (e.g., morphine) acts unsatisfactorily, a pain associated with diabetic neuropathy, or the like.</p>
申请公布号 WO2008111668(A1) 申请公布日期 2008.09.18
申请号 WO2008JP54709 申请日期 2008.03.14
申请人 ASTELLAS PHARMA INC.;AOKI, TOSHIAKI;TAMURA, SEIJI 发明人 AOKI, TOSHIAKI;TAMURA, SEIJI
分类号 C07D265/30;A61K31/5375;A61P3/10;A61P25/04 主分类号 C07D265/30
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