发明名称 TARGETED BINDING AGENTS DIRECTED TO PDGFR-ALPHA AND USES THEREOF
摘要 Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.
申请公布号 WO2008112003(A2) 申请公布日期 2008.09.18
申请号 WO2007US75117 申请日期 2007.08.02
申请人 ASTRAZENECA AB;LAING, NAOMI;KANG, JASPAL, SINGH;FOLTZ, IAN;GAZIT-BORNSTEIN, GADI;YANG, XIAO-DANG;CARTILAGE, SUE, A.;BLAKEY, DAVID, CHARLES 发明人 LAING, NAOMI;KANG, JASPAL, SINGH;FOLTZ, IAN;GAZIT-BORNSTEIN, GADI;YANG, XIAO-DANG;CARTILAGE, SUE, A.;BLAKEY, DAVID, CHARLES
分类号 C07K16/28;A61K39/395;C07K16/00 主分类号 C07K16/28
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