ENDOPHYTIC STREPTOMYCETES, COMPOUNDS DERIVED THEREFROM, AND METHODS OF THEIR USE

摘要

The present disclosure relates to an isolated strain of a Streptomyces spp. that are endophytes of dicotyledonous plants and to methods for selecting such strains. The present disclosure also relates to compounds having biological activity selected from the group consisting of munumbicin E-4 and munumbicin E-5, and biologically active derivatives thereof. Also provided are compositions of such compounds and methods of protecting plants against attack by a plant pathogen, and methods of inhibiting bacterial growth, fungal growth, viral infection or spread, growth of parasitic organisms, and cancer cell growth with such compositions.